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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c37c05d0d11565d195f6acde0bb3a4c6c342cd45a856af09535bd5559514e9b' 
  AND token = 'xaDRvEdxFPXsjn50jcO3+4IJgmNxsXr4hWPJeqaUZfg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}