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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18407c46421b143371b13529fb9dbd625a2c383f1300204a79e5c58c2c58d3ff' 
  AND token = 'ZERbe1PHt1VOr1UQtx79FhSzoC7t6rPwgCYDzCEtgv8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}