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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4fbd632c05d75bd2969dcfd9ce164712043f3cd50e66870433ffbff960a570bf' 
  AND token = '5GOiW/1+KzmygWUBzNPIf/tDwDd4azoG3+iuaPvLNOw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}