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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1768e42f4822af4a320619de71bc47bce27d2c147623be5adc0abce42bf1853' 
  AND token = 'UQZ4AFlnKTUKnm6XtlqnTvtVyzW0TwQRdf2+TjUzih0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}