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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '303161ab2d147a5a466b62ac10fca638195dd316e5a118e3b819548d461b4f2d' 
  AND token = '1o5Xg/hB/2VmXhTcUR84DHrzSYrHSRf0icZ2kAhdxEk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}