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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65b4c59a8352b36e9b5b99980f1b426d65cf2100d091d19e1d0c03899a66b218' 
  AND token = 'ncV/VpNCXeGYmW/1cKA2n9OvXZKgQ+Jho/3Uk6pa5kY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}