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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d04a7ea7626e839e1a533b30ccc9e03744d71075f17dd47c65aee3b79e6eeda' 
  AND token = 'VCqdKV1avRv8zEQzLnt8PGme/2daJOYFbGldzOkhY84=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}