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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2057bed4b9aa11216c4e4e046c2f9ec7e0f910c932c586f69d87c5920648957a' 
  AND token = '7j2Mc3YmfzXS/d57Nb+Zu524VY2dRD1xwMaHm8Ayr3c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}