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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '781c6c95fb69cc7baaa354de97f0884efe8ae5a32833a2022a3fa13a1e6ea0c5' 
  AND token = '1zS1nuo2i0LzMW9jzJTpKaGqsX0G0WdA/jpZW53XQAc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}