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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c82b1c1dcb87fd9e70469dee146ff4b9d7b90f74e7f332189cb1d98d59556c91' 
  AND token = 'A3eGqCbhO24hPx0BBcrS2uA+KJcYyIwmFIQ0lkBklNM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}