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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5046c2b9045c55a2b742595617abb808c0aa9eb8b168e8358e0739363e291a8d' 
  AND token = 'Y1wMP70n5VLpOZaYN2Z/qRfFMUEsGLFiDhX25b099jA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}