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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '158a060ffa8f0025184a5815dd6eccf002ab7907fde2448c2bb0b83bc8b0437a' 
  AND token = 'irqWLM8z73f+X5cQuzSwEg1tymbX/52zjRGCyIQXt34=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}