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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49d5e61b6072477a8f7188e7f44cdb9cb2f4e17aca08007a63ca60554e3e4cc4' 
  AND token = 'dxe47UHQP8b2rdNf+8QzuPhbXVlM9ENUhaJxrk97qmo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}