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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e543475db4db646278b421e5608364a51fd2813b140e99d72d7b433f3b0d068c' 
  AND token = '8+XBNCbf0ivo4aKYJS2UO9TMQ5Vk7Nu8WDdadD+W92A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}