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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6512406e27ea82ede14190d9afacabf2981738e65d82da219a152c52a1f40545' 
  AND token = 'K4rxCjWxPLTIyt2oV0oAn9fdPuHY35icMsR1SbRE3ZY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}