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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74f2cd1778f431d0686f423431199dfffe1f4639e6047d16778e10077da1c43a' 
  AND token = 'dREpyj0rzBZJnU/qA5fkVBxOFTrOWnqjDoHmUtOiRJg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}