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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21b98cd99f3c3acade1d6ea1b304346351ce4b4413cedc4bd4df470b11db1557' 
  AND token = 'akwU3n3TDlm1fNWVn1uXsqsHZ+5Bbt4SLCErU2AHzik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}