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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '149eed2f7b4c1cb3bdc22de366edb75ec499ac2df6c5a89131824082c8339576' 
  AND token = 'jXFKSvODI7K4bvIw8pNMxLX4edCrNDWsFFJrs9Ws4uU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}