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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c2e3a1afddfed26998f670038af806c053f7b3039499150f3bad0613e258112' 
  AND token = '6IcYyGvHh9M6foZezZIIaeTl0DsGVgQs0O5zUeda4Xo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}