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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c5d663c11517a0eb5ce39168f0a4ebdec32107491f825b07034cebb62091268' 
  AND token = 's9W9t7C2qKiS8BJdYOm8SPwqWdTnR2+u7JVT5kIw21s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}