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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c6a1a7a016350507b8d16063670810186dc2b5be1fd9c63d963ea4d6035a46f' 
  AND token = 'TpsAfdsZTN4aqNfzYDksmnur5EnEwuqCyAyNJyLfRsw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}