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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3623337e5a15865069e58e8b3a8195a45bf865afd073d252f6a984361604e21f' 
  AND token = 'I5mvWN8up5oCcqx1p8z2OHrr1rUA82nacmZWLIr/+vY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}