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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c4a9410b51ed75e228f3c81718ef3242c40467e104a8ac26fe211e23a6afe04' 
  AND token = 'apl6Ubyp/NjptwNzo7+Sx7I5vZ8vcGbd6rnPvj1frrE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}