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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f728369685ad213437c0859ab3c7e805f781c438af2c7afaaee22189a847afc' 
  AND token = '0w6Bk2r5afbYM4ipnsVnf7oRAVPcDNb6Zld09PY6hCU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}