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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d0111ac03b2922d7315e479bbe8a629a50e641277ac3e4b748a43336eb7da9a' 
  AND token = 'YkquDVpptYRzjjdFFZT0pdV9Yyk3kGOv+SYbI/dG6f8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}