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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6b12e3b16653d5ff2940d8a895810c45c582b4b07b43338ace894bd546f9fc4' 
  AND token = 'LjesADUTdUH4j8CJOqQcrUIo3RM7/vmOfJlasAMu4JA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}