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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c321e5bb5341af5c23911a32cfdb6008b4eeb5a18a2b34992d3706df58c8d7e' 
  AND token = 'qJJvkbJTb3DhGfjcFErJFP66SraaKObqkERwcstvgeI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}