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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd6c6845207029d6080bd9c33c3fbdf738f45d201b17af8a80a58e5c53d2d6b2' 
  AND token = 'SxA7fAjw74HZmMtO11rfseyBszlq7Zjf7P1rPHwZQis=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}