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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21709166c66f8f8d83255cac9b3e08c0a70fbe8675c7b975e2ab4e483bd9a8dd' 
  AND token = '3JbyDKpcqvNj5x1rbCxOdjEoOcgeCne4f14TCkZUigA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}