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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee8f0c0ceb455c624f0c51aabb4f21c216dbea1383a57d8a00b67e9dd88d9f77' 
  AND token = '3qqq1Gek/nDbz5fmDDy/7CAMuldWnBvL2C3NVe4jRl4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}