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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4842042d0e9627d4d6df5cf6c712cee20b8ef76ebf97bad0e4ff8648ffc2cd51' 
  AND token = '5QmMYCoklsOJ7I6Q9ER9efCF5xaiqlK9PidnNCHw0KM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}