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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8a7cdd1828b2026f2c55bb0604656bde3ee2e6f86a21440735783138cf9e43c' 
  AND token = 'N7U9O5PjzX4kBKsHdNpBlCIkY+yGIcdROd4pmdt5PGA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}