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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '820afda8c3428978635a372d9faa38dff4ec89e8fc153d04ef2b09c2ca1ec646' 
  AND token = 'ec3pd1gUmWy0tV3Ig54XaD7jrwIce2fnzU5A4CAQFKo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}