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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8815899d8af2c865e4984c9509e492b1b91338f47e232047f9aceb844e31a508' 
  AND token = '0zQkDPd9YrM5TiD7DlaASO1CJdGwpAB8LZTPj9+xzM8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}