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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df723124ceb656714421355c49d1015e81cc62acc4d030170b374054e3ed4989' 
  AND token = 'UfxNC8mg+3sTz9gvZ9DiL2XZH6kvoZOeTjQTkHHXkx0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}