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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5b1d64cafa024c4ca61ed14093d0687699f4b97745e3642b670649424bf6203' 
  AND token = 'wpaz8SWOsA/DF8X6be/XFi4J2wh5zLAS9QuKRUm1h0E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}