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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c45b9ed4b1a272f92c3b4311eb6f2805809e762d731a3f5c5ae33b54d32263b' 
  AND token = 'T82irUiJi2+SLPE41GY8sIWLE3D44pHtQ+fAAN4yPc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}