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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dc49d3151a04d9e419ca4ec71901cb79dafc18158f199d0e77ed44e53da57c47' 
  AND token = '8s2lYt0xd5Y0NxNB/Emlgtezi1ryB4dNb5iObieVgUs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}