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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b567e0a01a49bdef5a3900dea0f24f17e863f71f37a0b41cafff8381c96735d' 
  AND token = 'yfPH5ZZ2NThZxCMEAGgq34Y0qb2OwQx5C4gfRZweYRc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}