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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf51eda7f8621266160283e22a106802390d8b52ec4b2c893ef0f2e7b900b937' 
  AND token = '+Db8eQFS7oiXTViUVFz6+M74JC6qxGVrM4Y0MJVxRYM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}