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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0408b4b9af91a3b226a49435bcf159cec4a892c483667b4bb1fb716de18f9b77' 
  AND token = '5CQEp8G2uwr5dFlfet533wwIvascjFHyieoktb5cID8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}