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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fec0993d039b585b851deb7f461c5146b9ad7f40eda06b4fdd155dae1742434b' 
  AND token = 'HcSAzTt0jNo+eEdCA2vZzw4o6kPZmDgswIx1BzP5YOA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}