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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e377b2165215f7b2c27d11bc646320443a597e427a0fc465622e755c9ed11b68' 
  AND token = 'MA3JtzDm6w+R21GPMet6sp0kc+7cJ8BJdpnm1lZ5DrM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}