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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f63875744c239afe2c9c264b2d20e6ee7eeea943c5b05f027ddb337f70017dc0' 
  AND token = 'axW1EqM6qdQ1PsUwhQic4gviV1xM1Rt2ws25S+4Cb/Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}