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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c47510139f1fe95add7b6e8ddc60b2cc9c2609e8249568a5d7f50120017a197' 
  AND token = 'vv5V8ETACIa5yrfFgYwLRdgChnaGvuk3fDglz42jINs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}