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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a1b86022c0f52badc038186eda95f01d2bef8577c91cf3b4384c10f1b4d3de8' 
  AND token = 'Ok3gnX996nX9RMTOC2+UmK2AM7mOW/BXn7mWW/65J2E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}