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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7731185f3f039622f70e00f44efe0e2f7a8afe70d1d252b73875931d31bad949' 
  AND token = '+6onuawUsskhjTP8du18Khpk1VKtre6Nbbt32p1bwHw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}