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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8308e541f6f7edb9dbfe6d4e32e404449c5b55f2e1a494cdd56436d2c3c235f4' 
  AND token = 'tTlxLy2Rcm/EO0K6fmpbFOTh/coFKuswAColznK3Cew=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}