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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '900d7a8e5622e8ee589c623e91e2454e8aad3fe2c44e1fed96952c076b69e261' 
  AND token = 'F/PqQSbKceUw00MHfRAMReaGrYYuUNsYDrl4z6ww8NY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}