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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ac8fc63dff6c6a70e59944788392a1501f85baf40a610ded855c19448dd9bb1' 
  AND token = 'sSHHZbtVXewRh7OhSYFjdCiKlwUlF1SR8nCa67jBSsg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}